최철수 교수 연구실
article|
gold
·인용수 1
·2025
ARHGEF3 coordinates adipocyte hypertrophy and differentiation through dual YAP-RhoA and PPARγ activation
Sana Abdul Khaliq, Shi‐Young Park, Syeda Maham, Yoonil Cho, Miseon Lee, Seungyoon Nam, Je Kyung Seong, Jie Chen, Cheol Soo Choi, Mee‐Sup Yoon
IF 13Journal of Advanced Research
초록
ARHGEF3 emerges as a pivotal regulator of adipocyte dynamics by coordinating YAP-RhoA signaling and enhancing PPARγ activity. These findings offer novel therapeutic insights for addressing obesity and related metabolic disorders.
키워드
RHOADual (grammatical number)AdipocytePeroxisome proliferator-activated receptorMuscle hypertrophyCell biologyInternal medicineChemistryEndocrinologyMedicine