Spatial and temporal changes in the PGE2 EP2 receptor in mice hippocampi during postnatal development and its relationship with cyclooxygenase-2.
Hyo Young Jung, Woosuk Kim, Kyu Ri Hahn, Sung Min Nam, Sun Shin Yi, Hyun Jung Kwon, Min Soo Kang, Jung Hoon Choi, Dae Won Kim, Yeo Sung Yoon, In Koo Hwang
PubMed
초록
EP2 decreases with age, which is expressed in DCX-immunoreactive neuroblasts in the dentate gyrus. This suggests that EP2 is closely linked to structural lamination and adult neurogenesis in the dentate gyrus.
키워드
Dentate gyrusProstaglandin E2 receptorDoublecortinSubgranular zoneGranule cellNeurogenesisBiologyEndocrinologyHippocampal formationInternal medicine