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Additional file 1 of SSEA3 and CD105 positivity are associated with the treatment potency of human neural crest-derived nasal turbinate stem cells for Alzheimer’s disease
Jung Yeon Lim, Jung Eun Lee, Minho Lee, Haewon Shim, S Park, Soon A Park, Sin-Soo Jeun, Sheng-Min Wang, Sunghwan Kim, Seung Ho Yang, Hyun Kook Lim, Sung Won Kim
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Additional file 1. Fig. S1. Quality control and clustering of integrated scRNA-seq data from AD-COs (#1–2) and NAC-COs (#1–2). Fig. S2. Characterization of AD-COs and NAC-COs by single-cell transcriptomic profiling. Fig. S3. Representative Ca2+ oscillation traces in NAC-CO and AD-CO#1 cocultured with either NTSCs-H or NTSCs-SC for 5–6 days. Fig. S4. Presence of Muse cells (SSEA3+/CD105+) populations in initially purified Muse cells from NTSCs and in cultured Muse cells (NTSCs-SC). Table S5. Summary of therapeutic effects according to Muse cell proportion in NTSCs.

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PotencyTranscriptomeCellDiseaseCell cultureEndoglinMesenchymal stem cell
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