김완수 교수 연구실
article|
인용수 2
·2025
PRPF4 Knockdown Suppresses Glioblastoma Progressionviathe p38 MAPK and ERK Signaling Pathways
Wansoo Kim, Song Park, Seung Hyun Han, Hee-Yeon Kim, Seoung-Woo Lee, Dae‐Hwan Kim, Soyoung Jang, Jin‐Kyu Park, Jee Eun Han, Choonok Kim, Junho Cho, Ethan Seah, Jiyeon Lee, Zae Young Ryoo, Seong‐Kyoon Choi
Anticancer Research
초록
PRPF4 knockdown inhibits GBM progression by reducing p38 MAPK and ERK signaling cascade with metabolic alterations. Targeting PRPF4 may offer novel therapeutic strategies for GBM treatment.
키워드
Gene knockdownGlioblastomaMAPK/ERK pathwayCancer researchSignal transductionp38 mitogen-activated protein kinasesMedicineCell biologyBiologyApoptosis