Anti-Tumor Efficacy of Oleuropein-Loaded ZnO/Au Mesoporous Silica Nanoparticle in 5-FU-Resistant Colorectal Cancer Cells
Sang Mi Park, Da Yeon Kim, Kyeong Hyeon Lee, Yong‐Il Shin, Sang-Cheol Han, Sang‐Mo Kwon
IF 6.5International Journal of Nanomedicine
초록
ZnO/Au/OLP MSNs exhibited anti-cancer activity by upregulating necrosis. These results revealed that ZnO/Au/OLP MSNs are a novel drug delivery system for 5-FU CRC therapy.
키워드
Mesoporous silicaMaterials scienceNanomedicineBiocompatibilityCancer cellDrug deliveryReactive oxygen speciesCytotoxicityBiophysicsCancer research