Eosinophil‐derived interferon‐γ drives transmembrane protein 119–induced new bone formation in chronic rhinosinusitis with nasal polyps
Sungsin Jo, Bong Joon Jin, Seung Hoon Lee, Hye‐Ryeong Jo, Joo Mi Park, Kyung‐Gyun Hwang, Mina Rho, Tae‐Hwan Kim, Seok Hyun Cho
IF 6.4International Forum of Allergy & Rhinology
초록
Eosinophil-derived IFN-γ promotes the bone-forming activities of sinus bone cells via the STAT1-TMEM119 signaling pathway. Interleukin-4-eosinophil-IFN-γ axis may be crucial for TMEM119-mediated new bone formation in CRSwNP.