AIMP2 accumulation in brain leads to cognitive deficits and blood secretion in Parkinson’s disease
Heejeong Kim, Jeong‐Yong Shin, Sangwoo Ham, Ji Hun Kim, Gum Hwa Lee, Nae‐Eung Lee, Hee-Tae Kim, Seok Hyun Cho, Sang Seong Kim, Yunjong Lee
IF 7.5Journal of Translational Medicine
초록
The pathological role in the hippocampus and the cell-to-cell transmissibility of AIMP2 provide new therapeutic avenues for PD treatment, and plasma AIMP2 combined with α-synuclein may improve the accuracy of PD diagnosis in the early stages.
키워드
DiseaseMedicineSecretionCognitionParkinson's diseaseNeuroscienceBioinformaticsImmunologyBiologyInternal medicine