김종일 교수 연구실
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·인용수 6
·2025
Novel anti-CD73-IL-2v bispecific fusion protein augments antitumor immunity by alleviating immunosuppressive adenosine pathways in CD8+ T cells
Kayoung Shin, Min Park, Seoho Kim, Haejong Lee, Yuseong Lee, Jong‐Il Kim, Suyoun Park, Jisoo Kim, Kyungwha Lee, Chong Woo Park, Jihyun Kim, Eun Jin Lee, Hyuckjun Mok, Sung‐Man Oh, Sanghee Lee, Young Min Oh, Won‐Jae Lee, Yaein Amy Shim, Young-gyu Cho, Junsik Park, Jung-Yun Lee, Young Jun Koh, Kook Hwan Kim, Myoung Ho Jang
IF 10.6Journal for ImmunoTherapy of Cancer
초록
GI-αCD73/IL-2v bispecific protein is a novel and potent immunocytokine with significant antitumor immunity through cis-binding on CD8<sup>+</sup> T cells.
키워드
CD8Tumor microenvironmentAdenosineCancer researchImmunotherapyT cellImmune systemCytotoxic T cellCancer immunotherapyImmunology