정영훈 교수 연구실
article|
gold
·인용수 9
·2024
KCTD17-mediated Ras stabilization promotes hepatocellular carcinoma progression
Young Hoon Jung, Yun Ji Lee, Tam Dao, Kyung Hee Jung, Junjie Yu, Ah‐Reum Oh, Yelin Jeong, HyunJoon Gi, Young Un Kim, Dongryeol Ryu, Michele Carrer, Utpal B. Pajvani, Sang Bae Lee, Soon‐Sun Hong, KyeongJin Kim
IF 16.9Clinical and Molecular Hepatology
초록
KCTD17 induces the stabilization of Ras and downstream signaling pathways and HCC progression and may represent a novel therapeutic target for HCC.
키워드
Cancer researchHepatocellular carcinomaDownregulation and upregulationTumor progressionCarcinogenesisRegulator of G protein signalingUbiquitin ligaseCancerMedicineSignal transducing adaptor protein