Effective in vivo delivery of diphtheria toxin using protein cage nanoparticles for targeted cancer therapy.

CD7-Targeted Cytotoxic Potency of Diphtheria Toxin- and Ricin-based Immunotoxins in Targeted Therapy for T-Cell Acute Lymphoblastic Leukemia.

Protein Nanoparticles Simultaneously Displaying TRAIL and EGFR-Binding Ligands Effectively Induce Apoptotic Cancer Cell Death and Overcome EGFR-TKI Resistance in Lung Cancer.

Development of plug-and-deliverable intracellular protein delivery platforms based on  botulinum neurotoxin.

Protein cage nanoparticle-based NK cell-engaging nanodrones (NKeNDs) effectively recruit NK cells to target tumor sites and suppress tumor growth.

Kim, Y.,* Mun, J., Kim, E., Roh, H., Eom, S., Jun, H., Kim, H. J., Kim, M., Jeon, J. P., Park, S. H., Min, D.,* and Kang, S.,* Compact clustering of highly oligomerized anti-DR5 nanobodies effectively drives apoptotic cancer cell death, significantly suppressing tumor growth . Nano Today, 2025, 65, 102834.

Lee, H. B., Park, S. G., Kim, H. J., Jeon, J. P., Oh, S., Lee, S., Park, S. H., and Kang, S.,* CD7-Targeted Cytotoxic Potency of Diphtheria Toxin- and Ricin-based Immunotoxins in Targeted Therapy for T-Cell Acute Lymphoblastic Leukemia. Mol. Pharm., 2025, 22, 3255-3267.

Jun, H., Yeo, M., Jeon, J. P., Eom, S., Kim, H. J., Kim, Y., Jang, E., Park, S. H., Kim, E., and Kang, S.* CD13-targeting and TRAIL-displaying Protein Nanoparticles Effectively Induce Apoptotic Cell Death of Acute Myeloid Leukemia, Prolonging Survival in Mouse Models. Nano Today, 2024, 59, 102474.

Park, S. G.,# Kim, H. J.,# Lee, H. B., Eom, S., Jun, H., Jang, Y., Park, S. H.* and Kang, S.* Protein cage nanoparticle-based NK cell-engaging nanodrones (NKeNDs) effectively recruit NK cells to target tumor sites and suppress tumor growth. Nano Today, 2024, 54, 102075.

Choi, H., Yeo, M., Kang, Y., Kim, H. J., Park, S. G., Jang, E., Park, S. H.,* Kim, E.,* and Kang, S.* Lactate Oxidase/Catalase-displaying Nanoparticles Efficiently Consume Lactate in the Tumor Microenvironment to Effectively Suppress Tumor Growth. J. Nanobiotechnology, 2023, 21, 5.