김영준 교수 연구실
article|
hybrid
·인용수 1
·2025
Single-cell multiomic modelling of early metastatic events promoted by the extracellular matrix
Hyun Jin Lee, Jun Hyeong Lee, Junho Kang, Kyeonghui Kim, Youngwon Cho, Jihyun Park, Sang‐Hyun Song, Joonha Kwon, Young‐Joon Kim, Woong‐Yang Park, Tae‐You Kim, Jong-Eun Park, Pilnam Kim, Jung Kyoon Choi
British Journal of Cancer
초록
This study presents an advanced in vitro model that closely recapitulates in situ tumorigenesis and provides novel insights into the metastatic cascade. The pdECM system enables the reconstruction of EMT dynamics, highlighting the critical role of ECM composition in metastasis and offering a physiologically relevant platform for the development of targeted therapies.
키워드
Extracellular matrixMetastasisCarcinogenesisIn vitroMatrix (chemical analysis)Extracellular