이원석 교수 연구실
article|
gold
·인용수 2
·2025
Integrative multi-omics profiling identifies infiltrative hepatocellular carcinoma as an immunotherapy-resistant subtype with distinct molecular features
Won Suk Lee, Seonjeong Woo, Sung-Hwan Lee, Gae Hoon Jo, Il Hwan Kim, Hyeyeong Kim, Chansik An, Sanghoon Jung, Gwangil Kim, Haeyoun Kang, Beodeul Kang, Jung‐Sun Kim, Ho Yeong Lim, Incheon Kang, Hannah Yang, So Jung Kong, D. Son, Dong Jun Shin, Woo Young Kwon, Da‐Yeon Lee, Ju‐Seog Lee, Jun Ho Park, Youngsoo Kim, Sohyun Hwang, Chan Kim, Hong Jae Chon
Clinical and Molecular Hepatology
초록
Infiltrative HCC is a clinically aggressive and molecularly distinct subtype of advanced HCC. Morphological classification and type IV infiltrative signatures may guide risk stratification and therapeutic decision-making in advanced HCC treated with immunotherapy.
키워드
Hepatocellular carcinomaGene expression profilingHepatocellular cancerRisk stratificationCarcinoma