이재철 교수 연구실
article|
gold
·인용수 0
·2025
Divergence between neural and retinal lineage specification during human brain development by signal transduction
Ki Hong Nam, Sang Ah Yi, Linfan Xiao, Jae Sung Noh, Min Gyu Lee, Jae Kyun Jeong, Hyewon Jung, Ning‐Yi Shao, Jeung-Whan Han, Jaecheol Lee
IF 13Journal of Advanced Research
초록
Depletion of S6K1 signaling in the early stage of human brain development drives the formation of retinal cells distinct from cortical neurons. Our findings demonstrate that S6K1 signaling fine-tunes neuronal and retinal lineage specification during brain development.
키워드
RetinalLineage (genetic)Human brainNeural developmentSignal transductionBrain developmentDivergence (linguistics)