• Radiative flow of Jeffrey fluid due to the curved stretching surface is discussed. • First order chemical reaction, heat generation and Ohmic heating are taken into account. • The resultant systems are computed successfully through optimal homotopy analysis method (OHAM). Non-Newtonian materials have tremendous applications in industries, pharmaceuticals, manufacturing, substance designing and natural procedures. These materials are utilized in surface coating, penetrating activities, printing, cooling of metallic plates, damping and braking devices and many others. In view of such innovative applications here we communicate Soret and Dufour impacts in Jeffrey liquid flow caused by curved stretching surface. Thermal conductivity and mass diffusivity are temperature and concentration dependent respectively. Convective conditions are utilized. Radiation, first order chemical reaction, heat generation and Ohmic heating in present attempt are taken into account. Adequate transformations lead to resulting nonlinear differential system. Such system is computed successfully through Optimal homotopy analysis method (OHAM). Skin friction coefficient and Nusselt and Sherwood numbers in addition to velocity, temperature and concentration are examined. Here skin friction and temperature against magnetic field are opposite when compared with velocity. Temperature through Dufour number and radiation has increasing impact. Concentration for variable mas diffusivity and solutal Biot number has opposite response. An increase in thermal transport rate through Eckert number is detected. Sherwood number for curvature and variable mass diffusivity has opposite response. Larger approximation of reaction variable leads to decay concentration.