ROE LAB
연세대학교 본교(제1캠퍼스) 생화학과
노재석 교수
Leukemia Drug Resistance
DNA-Encoded Library Screening
BET Inhibitors
발행물
전체 논문
53
1
Engrailed-1 Promotes Pancreatic Cancer Metastasis
Jihao Xu, Jae-Seok Roe, EunJung Lee, Claudia Tonelli, Keely Y Ji, Omar W Younis, Tim D D Somervile, Melissa Yao, Joseph P Milazzo, Herve Tiriac, Anna M Kolarzyk, Esak Lee, Jean L Grem, Audrey J Lazenby, James A Grunkemeyer, Michael A Hollingsworth, Paul M Grandgenett, Alexander D Borowsky, Youngkyu Park, Christopher R Vakoc, David A Tuveson, Chang-Il Hwang
Advanced Science (Weinh), 2023
2
DW71177: A novel [1,2,4]triazolo[4,3-a]quinoxaline-based potent and BD1-Selective BET inhibitor for the treatment of acute myeloid leukemia
Imran Ali, Hyung Jin Cha, Byungho Lim, Chong Hak Chae, Jihyun Youm, Whui Jung Park, Sang Ho Lee, Jung Hwan Kim, Docgyun Jeong, Jae Kyung Lim, Yun-Ha Hwang, Jae-Seok Roe, Jae-Sung Woo, Kwangho Lee, Gildon Choi
European Journal of Medicinal Chemistry, 2023
3
Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction
Jumee Kim, Somi Kim, Seung-Yeon Lee, Beom-Ki Jo, Ji-Young Oh, Eun-Ji Kwon, Keun-Tae Kim, Anish Ashok Adpaikar, Eun-Jung Kim, Han-Sung Jung, Hwa-Ryeon Kim, Jae-Seok Roe, Chang Pyo Hong, Jong Kyoung Kim, Bon-Kyoung Koo, Hyuk-Jin Cha
Science Advances, 2023
4
Targeting FLT3-TAZ signaling to suppress drug resistance in blast phase chronic myeloid leukemia
Ji Eun Shin, Soo-Hyun Kim, Mingyu Kong, Hwa-Ryeon Kim, Sungmin Yoon, Kyung-Mi Kee, Jung Ah Kim, Dong Hyeon Kim, So Yeon Park, Jae Hyung Park, Hongtae Kim, Kyoung Tai No, Han-Woong Lee, Heon Yung Gee, Seunghee Hong, Kun-Liang Guan, Jae-Seok Roe, Hyunbeom Lee, Dong-Wook Kim, Hyun Woo Park
Molecular Cancer, 2023
5
Streamlined DNA-encoded small molecule library screening and validation for the discovery of novel chemotypes targeting BET proteins
Eunghee Hong, Kun-Liang Guan, Jae-Seok Roe, Hyunbeom Lee, Dong-Wook Kim, Hyun Woo Park
Molecular Cancer, 2023
6
A pipeline to characterize p53 effectors by integrative cistrome and transcriptome analysis in genetically-defined organoid model
June-Ha Shin, Hwa-Ryeon Kim, Jae-Seok Roe
Molecular Therapy Nucleic Acids, 2023
7
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination
Huh HD, Sub Y, Oh J, Kim YE, Lee JY, Kim HR, Lee S, Lee H, Pak S, Amos SE, Vahala D, Park JH, Shin JE, Park SY, Kim HS, Roh YH, Lee HW, Guan KL, Choi YS, Jeong J, Choi J, Roe JS, Gee HY, Park HW
Molecular Cancer, 2023
8
A TEAD2-driven endothelial-like program shapes basal-like differentiation and metastasis of pancreatic cancer
Hye-Been Yoo, Jin Woo Moon, Hwa-Ryeon Kim, Hee Seung Lee, Koji Miyabayashi, Chan Hee Park, Sabrina Ge, Amy Zhang, Yoo Keung Tae, Yujin Sub, Hyun-Woo Park, Heon Yung Gee, Faiyaz Notta, David A. Tuveson, Seungmin Bang, Mi-Young Kim, Jae-Seok Roe
Gastroenterology, 2023
9
LCK-Mediated RIPK3 Activation Controls Double-Positive Thymocyte Proliferation and Restrains Thymic Lymphoma by Regulating the PP2A-ERK Axis
Hwang SM, Ha YJ, Koo GB, Noh HJ, Lee AY, Kim BJ, Hong SM, Morgan MJ, Eyun SI, Lee D, Roe JS, Lee Y, Kim YS
Adv Sci (Weinh), 2022
10
RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment.
Park HH, Kim HR, Park SY, Hwang SM, Hong SM, Park S, Kang HC, Morgan MJ, Cha JH, Lee D, Roe JS, Kim YS
Mol Cancer, 2021