성제경 교수 연구실
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·인용수 1
·2025
Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated With Age-Related Corneal Dystrophies
Andrew Briere, Thao Vo, Benjamin A. Yang, David J. Adams, Takanori Amano, Oana V. Amarie, Zorana Berberovic, Lynette Bower, Steve D. M. Brown, Samantha Burrill, Soo Young Cho, Sharon Clementson-Mobbs, Abigail D’Souza, Mohammad Eskandarian, Ann M. Flenniken, Helmut Fuchs, Valerie Gailus-Durner, Yann Hérault, Martin Hrabě de Angelis, Jin Sun, Russell Joynson, Yeon Kyung Kang, Haerim Kim, Hiroshi Masuya, Hamid Méziane, Ki-Hoan Nam, Hyuna Noh, Lauryl M. J. Nutter, Marcela Pálková, Jan Procházka, Miles Joseph Raishbrook, Fabrice Riet, Jason Salazar, Radislav Sedlacek, Mohammed Selloum, Kyoung Yul Seo, Je Kyung Seong, Hae-Sol Shin, Toshihiko Shiroishi, Michelle Stewart, Karen L. Svenson, Masaru Tamura, Heather Tolentino, Sara Wells, Wolfgang Wurst, Atsushi Yoshiki, Louise Lanoue, K. C. Kent Lloyd, Brian C. Leonard, Michel J. Roux, Colin McKerlie, Ala Moshiri
IF 4.7Investigative Ophthalmology & Visual Science
초록
This study identified 14 genes linked to LACD in knockout mice, 12 of which are novel in corneal biology. These genes may serve as potential therapeutic targets for treating corneal diseases in aging human populations.
키워드
Knockout mouseBiologyGeneOphthalmologyCorneal dystrophyGeneticsCorneaMedicine