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Supplementary Figures 1 through 6, Supplementary Tables 2 and 2, and Supplementary Methods from Selective Inhibition of Pancreatic Ductal Adenocarcinoma Cell Growth by the Mitotic MPS1 Kinase Inhibitor NMS-P715
Roger B. Slee, Brenda R. Grimes, Ruchi Bansal, Jesse Gore, Corinne Blackburn, Lyndsey Brown, Rachel Gasaway, Jaesik Jeong, José Victorino, Keith L. March, Riccardo Colombo, Brittney‐Shea Herbert, Murray Korc
초록

<p>PDF - 1019K, Figure S1 The CIN70 signature predicts survival in PDAC patients. Figure S2 Murine PDAC KRC cells exhibit chromosome instability and evidence of a weakened SAC. Figure S3 Clonogenic survival of PANC-1 and BxPC3 cells treated with NMS-P715. Figure S4 Growth of human adipose stem cells (ASCs) in the presence of NMS-P715. Figure S5 Murine PDAC KRC cell growth is inhibited by NMS-P715. Figure S6 Inhibition of PDAC cell growth after pre-treatment with NMS-P715. Table S1 Chromosome stability in cell lines. Table S2 PDAC CIN25 genes ranked by Cox score Supplementary methods for gene expression and survival analyses.</p>

키워드
Clonogenic assayCancer researchCell growthBiologyMitosisPancreatic ductal adenocarcinomaCellInternal medicineMedicineCancer
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supplementary-materials
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2023

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