윤동호 교수 연구실
article|
인용수 14
·2022
Spinal orexin A attenuates opioid-induced mechanical hypersensitivity in the rat
Dong‐ho Youn, Jiyeon Jun, Tae‐Wan Kim, Ki Beom Park
IF 2.8The Korean journal of pain
초록
Spinal orexin A attenuates mechanical hyperalgesia induced by repetitive intradermal injections of DAMGO through OX1R. These data suggest that OIH can be potentially treated by activating the orexin A-OX1R pathway in the spinal dorsal horn.
키워드
DAMGODynorphinMedicineOrexinHyperalgesiaDynorphin AOpioidAgonistAnesthesiaOrexin-A