Medicinal Chemistry Lab.
광주과학기술원 본교(제1캠퍼스) 화학과
안진희 교수
Transcription Factor Interaction Dynamics
Zebrafish Drug Evaluation
Blood-Brain Barrier Permeability
발행물
전체 논문
11
1
Discovery of a peripheral 5HT2A antagonist as a clinical candidate for Metabolic Dysfunction-Associated Steatohepatitis
Haushabhau S. Pagire, Suvarna H Pagire, Byung-kwan Jeong, Won-il Choi, Chang Joo Oh, Chae Won Lim, Minhee Kim, Jihyeon Yoon, Seong Soon Kim, Myung Ae Bae, Jae-Han Jeon, Sungmin Song, Hee Jong Lee, Eun Young Lee, Peter Goughnour, Dooseop Kim, In-Kyu Lee, Rohit Loomba, Hail Kim*, Jin Hee Ahn*
Nature Communications, 2024
2
Design, synthesis, and biological evaluation of new 2,6,7-substituted purine derivatives as Toll-like receptor 7 agonists for intranasal vaccine adjuvants
Morgan Kim, Kyungseob Noh, Pyeongkeun Kim, Jaeho Kim, Byeong Wook Choi, Ravi Singh, Junho Choi, Soo Bong Han, Seong Soon Kim, Eun-Young Lee, Myung Ae Bae, Daeho Shin, Meehyein Kim*, Jin Hee Ahn*
J. Med. Chem., 2024
3
Preparation of pyrrolopyrimidine derivative for preventing or treating metabolic liver disease
Bae, Myung Ae, Ahn, Jin Hee, Yang, Jung Yoon, Shin, Dae Seop, Hwang, Kyu Seok, Kim, Seong Soon, Lee, Byung Hoi, Ahn, Se Hwan, Kim, Dong Gun, Heo, Ye Rim
, 2023
4
Synthesis and biological evaluation of xanthine derivatives with phenacyl group as tryptophan hydroxylase 1 (TPH1) inhibitors for obesity and fatty liver disease
Jihyeon Yoon, Won-Il Choi, Saravanan Parameswaran, Gwi Bin Lee, Byung Wook Choi, Pyungkeun Kim, Dae-Seop Shin, Ha Neul Jeong, Seung Mi Lee, Chang Ju Oh, Jae-Han Jeon, In-Kyu Lee, Myung Ae Bae*, Hail Kim*, Jin Hee Ahn*
Bioorg. & Med. Chem. Lett., 2023
5
Inhibition of PDK4 ameliorates renal ischemia-reperfusion injury by reducing succinate 3 accumulation during ischemia and preserving mitochondrial function during reperfusion
Chang Joo Oh, Min-Ji Kim, Ji-Min Lee, Dong Hun Kim, Il-Young Kim, Sanghee Park, Yeongmin Kim, Kyung-Bok Lee, Sang-Hee Lee, Chae Won Lim, Myeongjin Kim, Jung-Yi Lee, Haushabhau S. Pagire, Suvarna H. Pa
,
6
Inhibition of pyruvate dehydrogenase kinase 4 in CD4+ T cells ameliorates intestinal inflammation
Hoyul Lee, Jae Han Jeon, Yu-Jeong Lee, Mi-Jin Kim, Woong Hee Kwon, Dipanjan Chanda, Themis Thoudam, Haushabhau S. Pagire, Suvarna H. Pagire, Jin Hee Ahn, Robert A. Harris, Eun Soo Kim, In-Kyu Lee
Kidney International, 2023
7
Synthesis and Biological evaluation of Tyrosine derivatives as peripheral 5HT2A receptor antagonists for Nonalcoholic Fatty Liver Disease
Minhee Kim, Wonil Choi, Jihyeon Yoon, Byung-kwan Jeong, Suvarna H. Pagire, Haushabhau S. Pagire, Jungsun Park, Jung Eun Nam, Chang Joo Oh, Jae-Han Jeon, Seong Soon Kim, Byung Hoi Lee, Jin Sook Song, Myung Ae Bae, In Kyu Lee, Hail Kim, Jin Hee Ahn
Cellular and Molecular Gastroenterology and Hepatology, 2023
8
Novel Thioxothiazolo[3,4-a]quinazolin-5(4H)-one Derivatives as BKCa Channel Activators for Urinary Incontinence
Eun Jung Bae, Heeji Jo, Seong Soon Kim, Dae-Seop Shin, Jung Yoon Yang, Myung Ae Bae, Pyeonghwa Jeong, Chul-Seung Park, Jin Hee Ahn
Eur. J. Med. Chem., 2022
9
Identification of New Non-Blood-Brain Barrier Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty liver Disease
Suvarna H. Pagire, Haushabhau S. Pagire, Kun-Young Park, Eun Jung Bae, Kwang-eun Kim, Minhee Kim, Jihyeon Yoon, Saravanan Parameswaran, Jun-Ho Choi, Sungmi Park, Jae-Han Jeon, Jin Sook Song, Myung Ae Bae, In-Kyu Lee, Hail Kim, Jae Myoung Suh, Jin Hee Ahn
Molecules, 2022
10
Discovery and characterization of a potent activator of the BKCa channel that relieves overactive bladder syndrome in rats
avanan Parameswaran, Jun-Ho Choi, Sungmi Park, Jae-Han Jeon, Jin Sook Song, Myung Ae Bae, In-Kyu Lee, Hail Kim, Jae Myoung Suh, Jin Hee Ahn
Molecules, 2022