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·인용수 1
·2025
Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling (Adv. Sci. 31/2025)
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sang‐Hoon Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim
IF 14.1Advanced Science
초록
Nuclear TeNsioNIn article number 2502375, Dong-Hwee Kim, and co-workers present a mechanobiological mechanism of progerin-induced wrinkling of nuclear surface.They demonstrate a new biophysical aging process that the abnormal nuclear shape leads to the regulation of agingdependent changes of gene profiles.
키워드
Mechanosensitive channelsChromatin remodelingCell biologyChromatinMaterials scienceChemistryBiologyDNABiochemistry