Dr Shin reported receiving grants from the Ministry of Food and Drug Safety, the Ministry of Health and welfare, the National Research Foundation of Korea, and Government-wide R&D Fund for infectious disease research; grants from pharmaceutical companies including Amgen, Pfizer, Hoffmann-La Roche, Dong-A ST, Yungjin outside the submitted work. No other disclosures were reported. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.