In this study, a clinical trial was conducted to confirm the effectiveness of cosmetics containing Fermented Rhus verniciflua Stokes · Orostachys japonicus A. Berger Complex Extract (FRO) on acne skin improvement. The result is as follows: After 6 weeks of using FRO cosmetics, it was confirmed that acne comedones, papules, and pustules were significantly reduced. In addition, as a result of analyzing the change in acne status with the KAGS grade, the experimental group improved from M = 2.07 before the experiment to M = 1 after 6 weeks. In addition, the results of acne improvement satisfaction were statistically significant at the 2nd week (p<.01), 4th week (p<.04), and 6th week (p<.01) between the experimental group and the control group. In addition, as a result of analyzing the acne improvement effect of experts, it was statistically significant at the 2nd week (p<.001), 4th week (p<.001), and 6th week (p<.001) between the experimental group and the control group. Therefore, It was confirmed that Fermented Rhus verniciflua Stokes · Orostachys japonicus A. Berger complex extract (FRO) can be useful as a functional cosmetic because it has the effect of improving acne skin.