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·인용수 9
·2023
Resistance of hypervirulent Klebsiella pneumoniae to cathepsin B-mediated pyroptosis in murine macrophages
Jin Kyung Kim, Hui-Jung Jung, Miri Hyun, Ji Yeon Lee, Jong‐Hwan Park, Seong‐Il Suh, Won‐Ki Baek, Hyun Ah Kim
IF 5.9Frontiers in Immunology
초록
HvKp infection resulted in different levels of pyroptosis via the activation of cathepsin B-NLRP3-caspase-1 in murine macrophages. Therefore, the manipulation of pyroptotic cell death is a potential target for host response during hvKp infection in macrophages.
키워드
PyroptosisKlebsiella pneumoniaeMicrobiologyBiologyImmunologyGeneInflammationEscherichia coliInflammasome