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구성원
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·2025
Characteristic of pulmonary fibrosis using 1700nm swept-source polarization-sensitive OCT: a comparative study with second harmonic generation imaging
Jihun Kim, Yong-Jae Lee, Jı Eun Bae, Soo Han Kim, Chang Hyun Park, S. Lucia, Pilhan Kim, Tae Joong Eom
초록

We employed a 1700nm swept-source PS-OCT to image fibrous collagen in fibrotic lung tissue through phase retardation images. To confirm the fibrous collagen, we utilized SHG signal imaging from two-photon microscope. The SHG signal was generated specifically in fibrous collagen tissue. In conclusion, the comparison between the phase retardation images and SHG images demonstrated that the PS-OCT system can be useful in detecting pulmonary fibrosis.

키워드
Polarization (electrochemistry)Second-harmonic generationHarmonic analysisSecond-harmonic imaging microscopyHigh harmonic generationOpticsHarmonicPulmonary fibrosisMedicinePhysics
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article
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게재 연도
2025