구자현 교수 연구실
article|
hybrid
·인용수 76
·2015
PHLDA3 overexpression in hepatocytes by endoplasmic reticulum stress via IRE1–Xbp1s pathway expedites liver injury
Chang Yeob Han, Sang Woo Lim, Ja Hyun Koo, Won Kim, Sang Geon Kim
IF 25.8Gut
초록
ER stress in hepatocytes induces PHLDA3 via IRE1-Xbp1s pathway, which facilitates liver injury by inhibiting Akt.
키워드
Unfolded protein responseXBP1Endoplasmic reticulumATF6Liver injuryBiologyHepatocyteCell biologyCancer researchMolecular biology