article|
인용수 1
·2025
The long-term influences of age at injury on neuroinflammation and neuronal apoptosis following traumatic brain injury in pediatric and adult mice
Jin-Soo Park, Hyun-Jeong Park, Young Min Kim, Hyun-Seok Chai, Gwan Jin Park, Sang Chul Kim, Gyeong-Gyu Yu, Suk-Woo Lee, Hoon Kim
IF 2.3Clinical and Experimental Emergency Medicine
초록
Pediatric and adult mice exhibited significant time-dependent differences in neuroinflammation and apoptosis following TBI, with pediatric mice showing more intense early responses indicative of age-specific vulnerabilities in post-injury outcomes. Both age groups showed a significant but transient increase in HSP70 expression, suggesting an acute response to stress post-injury.
키워드
NeuroinflammationMedicineTraumatic brain injuryApoptosisTerm (time)NeuroscienceIntensive care medicineInternal medicineInflammationPsychiatry