Evaluation of the anti-cancer efficacy of lipid nanoparticles containing siRNA against HPV16 E6/E7 combined with cisplatin in a xenograft model of cervical cancer
Sung Wan Kang, Ok-Ju Kang, Ji‐Young Lee, Hye-Jeong Kim, Hunsoon Jung, Hongjoong Kim, Shin‐Wha Lee, Yong‐Man Kim, Eun Kyung Choi
IF 2.6PLoS ONE
초록
The combination of ENB101-LNP, which inhibits E6/E7 of HPV 16, with cisplatin, demonstrated significant anticancer activity in the xenograft mouse model of cervical cancer.