권도훈 교수 연구실
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인용수 0
·2023
MD simulations for "TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease"
Do Hoon Kwon, Feng Zhang, Brett A. McCray, Shasha Feng, Meha Kuma, Jeremy M. Sullivan, Wonpil Im, Charlotte J. Sumner, Seok‐Yong Lee
Zenodo (CERN European Organization for Nuclear Research)
초록
MD simulations for publication "TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease" on Nature Communications. Initial and last system snapshots of 8 simulation systems are provided: 1) GSK279-TRPV4 in GSK279 pose I, 2) GSK279-TRPV4 in GSK279 pose II, 3) GSK279-TRPV4-RhoA-GDP in GSK279 pose I, 4) GSK101-TRPV4, 5) GSK101-TRPV4-RhoA-GTP, 6) 4α-PDD-TRPV4 in 4α-PDD pose I, 7) 4α-PDD-TRPV4 in 4α-PDD pose II, 8) 4α-PDD-TRPV4 in 4α-PDD pose III.
키워드
GatingTRPV4GTPaseDiseaseBiophysicsChemistryComputer scienceNeuroscienceCell biologyPsychology