Platinum-Coated Porous Gold Nanorods in Methanol Electrooxidation: Dependence of Catalytic Activity on Ligament Size

Tri-Component Gold-Nickel-Silver Nanorods Leading to Multiple Surface Plasmon Bands

Synthesis of Hollow and Nanoporous Au/Pt Alloy Nanoparticles and their Electrocatalytic Activity for Formic acid Oxidation

Shape-controlled Synthesis of Pt Nanoframes

Comparison of the Catalytic Activity of Platinum-Coated Porous Gold Nanorods in Methanol Electrooxidation: Dependence of Catalytic Activity on Ligament Size

Porous Nanoframe for Gas Sensing

Open Facets: Efficient Gas-Phase Analyte Penetration

MOF-Integrated Nanosponges for Sensitive Gas-Phase SERS Detection

Detecting weakly adsorbing molecules via label-free surface-enhanced Raman scattering is addressed through the development of tricomponent substrates using dual-rim nanorings made of Au, Ag, and CuO, each with distinct functionalities. The CuO nanorings provide strong adsorption of carboxylates via chelating bonds, while Au and Ag nanorings enhance Raman scattering signals through strong coupling effects. These tricomponent assemblies allow effective Raman-based analysis of biomolecules, including amino acids, proteins, nucleobases, and nucleotides, demonstrating their potential for sensitive detection applications.

This study introduces annular Au nanotrenches, a novel class of nanoparticles with narrow circular nanogaps (~1 nm), designed for near-field focusing in surface-enhanced Raman scattering immunoassays for detecting SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). These nanotrenches achieved an exceptionally low detection limit of 1 fg/mL for spike glycoproteins, outperforming enzyme-linked immunosorbent assays by six orders of magnitude. Clinical testing on 50 samples demonstrated a sensitivity of 96% and a selectivity of 100%, representing the superior sensing capabilities of this approach compared to existing diagnostic methods.