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이승원 연구실
성균관대학교 의학과
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이승원 연구실

성균관대학교 의학과 이승원 교수

이승원 연구실은 의료 빅데이터와 인공지능을 기반으로 정밀의학, 질환 예측, 희귀질환 및 암 연구, 프라이버시 보존형 연합학습, 블록체인 기반 의료데이터 활용, 임상 적용형 디지털 헬스케어 서비스 개발을 수행하며, 실제 의료 현장에 적용 가능한 신뢰성 높은 의료 AI 기술과 융합형 전문 인재 양성을 함께 추진하는 연구실이다.

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의료 빅데이터 기반 정밀의학 및 질환 예측 thumbnail
의료 빅데이터 기반 정밀의학 및 질환 예측
주요 논문
3
논문 전체보기
1
article
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gold
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인용수 0
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2026
Federated Learning in Healthcare Ethics: A Systematic Review of Privacy-Preserving and Equitable Medical AI
Bilal Ahmad Mir, Syed Raza Abbas, Seung Won Lee
IF 2.7
Healthcare
<b>Background/Objectives</b>: Federated learning (FL) offers a way for healthcare institutions to collaboratively train machine learning models without sharing sensitive patient data. This systematic review aims to comprehensively synthesize the ethical dimensions of FL in healthcare, integrating privacy preservation, algorithmic fairness, governance, and equitable access into a unified analytical framework. The application of FL in healthcare between January 2020 and December 2024 is examined, with a focus on ethical issues such as algorithmic fairness, privacy preservation, governance, and equitable access. <b>Methods</b>: Following PRISMA guidelines, six databases (PubMed, IEEE Xplore, Web of Science, Scopus, ACM Digital Library, and arXiv) were searched. The PROSPERO registration is CRD420251274110. Studies were selected if they described FL implementations in healthcare settings and explicitly discussed ethical considerations. Key data extracted included FL architectures, privacy-preserving mechanisms, such as differential privacy, secure multiparty computation, and encryption, as well as fairness metrics, governance models, and clinical application domains. <b>Results</b>: Out of 3047 records, 38 met the inclusion criteria. The most popular applications were found in medical imaging and electronic health records, especially in radiology and oncology. Through thematic analysis, four key ethical themes emerged: algorithmic fairness, which addresses differences between clients and attributes; privacy protection through formal guarantees and cryptographic techniques; governance models, which emphasize accountability, transparency, and stakeholder engagement; and equitable distribution of computing resources for institutions with limited resources. Considerable variation was observed in how fairness and privacy trade-offs were evaluated, and only a few studies reported real-world clinical deployment. <b>Conclusions</b>: FL has significant potential to promote ethical AI in healthcare, but advancement will require the development of common fairness standards, workable governance plans, and systems to guarantee fair benefit sharing. Future studies should develop standardized fairness metrics, implement multi-stakeholder governance frameworks, and prioritize real-world clinical validation beyond proof-of-concept implementations.
https://doi.org/10.3390/healthcare14030306
Health care
Implementation
Stakeholder
Data sharing
Corporate governance
Key (lock)
Cryptography
Information privacy
2
article
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gold
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인용수 0
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2026
Embodied Artificial Intelligence in Healthcare: A Systematic Review of Robotic Perception, Decision-Making, and Clinical Impact
Bilal Ahmad Mir, Dur E. Nishwa, Seung Won Lee
IF 2.7
Healthcare
<b>Background</b>: Embodied artificial intelligence (EAI), integrating advanced AI algorithms with robotic platforms capable of sensing, planning, and acting, has emerged as a transformative approach in healthcare delivery. This systematic review synthesizes evidence on robotic perception, decision-making, and clinical impact of EAI systems in healthcare settings. <b>Methods</b>: Following PRISMA 2020 guidelines, we searched PubMed/MEDLINE, Scopus, Web of Science, IEEE Xplore, and ACM Digital Library for studies published between January 2020 and August 2025. Seventeen studies met eligibility criteria, spanning four domains: surgical assistance, rehabilitation, hospital logistics, and telepresence. The protocol was prospectively registered in PROSPERO under ID: CRD420261285936. <b>Results</b>: Perception architectures predominantly employed multimodal sensor fusion, combining vision with force/torque, depth, and physiological signals. Decision-making approaches included imitation learning, reinforcement learning, and hybrid symbolic-neural control. Key findings indicate that surgical robots demonstrated consistency advantages in specific experimental tasks, rehabilitation robotics produced statistically significant improvements (SMD = 0.29) across 396 randomized controlled trials, and both logistics and telepresence systems achieved very high operational success levels. Nonetheless, important barriers remain, including limited external validation, small sample sizes, and insufficient cost-effectiveness data. <b>Conclusions</b>: Future research should prioritize standardized benchmarks, prospective multicenter trials, and patient-centered outcome measures to facilitate clinical translation of EAI technologies.
https://doi.org/10.3390/healthcare14050572
Robotics
Transformative learning
Robot
Protocol (science)
Health care
Systematic review
Empathy
Rehabilitation robotics
3
article
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gold
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인용수 0
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2026
Blockchain for smart healthcare: A systematic review of security, interoperability, and AI–IoT integration
Syed Raza Abbas, Zeeshan Abbas, Mobeen Ur Rehman, Seung Won Lee
IF 3.3
Digital Health
Background Blockchain is increasingly explored as an infrastructure to mitigate data fragmentation, security incidents, and limited patient control in digital health ecosystems. This systematic review analyzed applications of blockchain in smart health systems, with a focus on security models, interoperability approaches, and integration with Internet of Things (IoT) and artificial intelligence (AI). Methods Following PRISMA 2020, PubMed, IEEE Xplore, ScienceDirect, Springer, and Google Scholar were searched for studies published between January 2019 and August 2025 using a predefined strategy combining the terms (“blockchain” OR “distributed ledger”) AND (“healthcare” OR “medical” OR “health records”) AND (“security” OR “privacy” OR “interoperability”); of the 1847 records screened, 26 studies met the eligibility criteria. Results Across these studies, blockchain most consistently strengthened electronic health record management by providing cryptographic access control, tamper-evident and immutable audit trails, and support for cross-institutional data exchange. In four multi-institutional settings, coupling blockchain with AI enabled privacy-preserving federated learning for collaborative diagnostics without centralized data pooling. However, several technical and regulatory constraints were reported, including limited scalability (median throughput <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" overflow="scroll"> <mml:mo>≈</mml:mo> </mml:math> 850 transactions/second vs. &gt;10,000/seconds typically required for national infrastructures), high energy consumption in proof-of-work based schemes, and unresolved tension between immutable ledger storage and data protection rules such as the General Data Protection Regulation “right to be forgotten.” Conclusion Overall, the evidence indicates that blockchain is a credible enabler of secure, interoperable, and patient-governed health data sharing, provided that future deployments incorporate Layer-2 or comparable scalability mechanisms, adopt energy-efficient consensus protocols, and operate within clearer regulatory guidance on the permanence of clinical data.
https://doi.org/10.1177/20552076261420985
Blockchain
Interoperability
Scalability
Enabling
Data management
Data anonymization
Audit
Cryptography
The Internet
정부 과제
21
과제 전체보기
1
2025년 6월-2028년 12월
|1,832,668,000
페놈데이터 기반 AI 생애 전주기 건강위험 예측·관리 초격차 기술 개발
1. 예측 및 관리 기술 개발- 비만, 대사성 간질환, 고혈압, 당뇨병 등 4대 만성질환 중심의 다질환 예측 AI 모델 개발- 암, 혈관질환, 콩팥병 등의 합병증 예측 알고리즘 구축- 단기/중기/장기 예측 모델로 개인 건강 상태의 변화 리스크 정밀 예측2. Agentic AI 기반 서비스- 사용자의 건강 목표에 맞춰 계획-실행-학습-최적화를 수행하는 자율형...
페놈데이터
정밀의료
오믹스
에이전틱인공지능
인공지능기반건강예측
2
2025년 3월-2029년 12월
|391,670,000
FLAME-ARK 솔루션 개발 실증: 회송/전원 지원 AI
1. 의무기록 기반 기관 맞춤형 전원/회송 서류 생성 서비스 개발 및 실증 ○ 목표: 환자 회송 및 전원 시 의무기록을 기반으로 자동으로 회송서와 전원의뢰서 초안을 생성하는 서비스를 개발하고, 실제 임상 현장에 적용하여 상용화. 이를 통해 의료진의 업무 부담을 줄이고 환자 회송 및 전원 프로세스의 효율성과 정확성을 향상. - EMR 기반 데이터베이스 구축...
연합학습
인공지능
파운데이션 모델
알고리즘
플랫폼
3
2025년 3월-2029년 12월
|1,000,000,000
의료 인공지능 특화 융합인재 양성 사업
○ 본 사업의 목적은 바이오헬스 산업의 혁신과 보건의료 서비스의 질적 향상을 위해 인공지능 기술을 접목한 전문 인재를 양성하는 데 있음. 이에 따라, 의료 AI산업에서 요구하는 핵심 역량을 반영하여'융합형 인재, 혁신적 인재, 실무적 인재, 창의적 인재'라는 네 가지 인재상을 설정하고 의료 AI산업의 지속적인 발전과 글로벌 경쟁력 강화를 위해 융합적 사고,...
의료인공지능
인공지능
의료정보
신약·치료제
의료기기
최신 특허
특허 전체보기
상태출원연도과제명출원번호상세정보
등록2021인공지능 기반의 암종별 타겟 선정 및 암종 예측 방법1020210120460
등록2021인공지능 기반의 증상 및 질환 매칭을 위한 챗봇 서비스 제공방법1020210114558
등록2020미세 먼지를 포함하는 대기 오염 물질에 대한 인체 위험도를 추정하기 위한 빅데이터 분석 방법1020200047895
전체 특허

인공지능 기반의 암종별 타겟 선정 및 암종 예측 방법

상태
등록
출원연도
2021
출원번호
1020210120460

인공지능 기반의 증상 및 질환 매칭을 위한 챗봇 서비스 제공방법

상태
등록
출원연도
2021
출원번호
1020210114558

미세 먼지를 포함하는 대기 오염 물질에 대한 인체 위험도를 추정하기 위한 빅데이터 분석 방법

상태
등록
출원연도
2020
출원번호
1020200047895