RESULT OF A TRIAL FOR EVALUATING ADDITIONAL BENEFIT OF CILOSTAZOL TO DUAL ANTIPLATELET THERAPY IN PATIENTS WITH LONG OR MULTIVESSEL CORONARY ARTERY DISEASE UNDERWENT BIOLIMUS–ELUTING STENT IMPLANTATION (ABCD TRIAL)
Young Jin Youn, Jun‐Won Lee, Sung Gyun Ahn, Seung–Hwan Lee, Junghan Yoon, Bong‐Ki Lee, Byung Ok Kim, Cheol Woong Yu, Dong Woon Jeon, Hyuck Moon Kwon, Hyun Min Choe, Jang Hyun Cho, Keum Soo Park, Kook Jin Chun, Kyoo Rok Han, Kyung Soo Kim, Myeong Kon Kim, Myung Ki Hong, Sang Yong Yoo, Seung‐Woon Rha, Young Joon Hong, Yun Hyeong Cho
Combined Assessments of Biochemical Markers and ST-Segment Resolution Provide Additional Prognostic Information for Patients With ST-Segment Elevation Myocardial Infarction
Jong Shin Woo, Jin Man Cho, Soo–Joong Kim, Myeong Kon Kim, Chong Jin Kim
Korean Circulation Journal
Assessment of biomarkers upon admission and ST-segment resolution are strong predictors of clinical outcomes. The combination of these data provides additive information about prognosis at an early point in the disease progression and further improves risk stratification for STEMI.
AS-012 Clinical Outcomes of Primary Percutaneous Coronary Interventions for Acute Myocardial Infarctions in Hospitals With and Without Onsite Cardiac Surgery Backup
Min Kyeong Kim, Weon Kim, Sang Jin Ha, Tae Kyung Yu, Jong Shin Woo, Soo–Joong Kim, Myeong Kon Kim, Kwon Sam Kim
Quantification of regional calcium burden in chronic total occlusion by 64-slice multi-detector computed tomography and procedural outcomes of percutaneous coronary intervention
Jung Rae Cho, Young Jin Kim, Chul‐Min Ahn, Jae-Youn Moon, Jung‐Sun Kim, Hyun Soo Kim, Myeong Kon Kim, Young‐Guk Ko, Donghoon Choi, Namsik Chung, Kyu-Ok Choe, Won-Heum Shim, Seung‐Yun Cho, Yangsoo Jang
Estrogen Receptors α and β Mediate Contribution of Bone Marrow–Derived Endothelial Progenitor Cells to Functional Recovery After Myocardial Infarction
Hiromichi Hamada, Myeong Kon Kim, Atsushi Iwakura, Masaaki Ii, Tina Thorne, Gangjian Qin, Jun Asai, Yoshiaki Tsutsumi, Haruki Sekiguchi, Marcy Silver, Andrea Wecker, Evelyn Bord, Yan Zhu, Raj Kishore, Douglas W. Losordo
Circulation
Both ER alpha and ER beta contribute to E2-mediated EPC activation and tissue incorporation and to preservation of cardiac function after myocardial infarction. ER alpha plays a more prominent role in this process. Moreover, ER alpha contributes to upregulation of vascular endothelial growth factor, revealing possible mechanisms of an effect of E2 on EPC biology. Finally, these data provide additional evidence of the importance of bone marrow-derived EPC phenotype in ischemic tissue repair.
Apical Hypertrophic Cardiomyopathy: Clinical and Echocardiographic Follow Up
Myeong Kon Kim, Nam Sik Chung, Jong‐Won Ha, Se‐Joong Rim, Nam Ho Lee, Shin Ki Ahn, Tae Yong Kim, Moon‐Hyoung Lee, Won Heum Shim, Seung Yun Cho, Sung Soon Kim
Tae Yong Kim, Dong Il Lee, Bum‐Kee Hong, Donghoon Choi, Se‐Joong Rim, Myeong Kon Kim, Dong Soo Kim, Yangsoo Jang, Namsik Chung, Won Heum Shim, Seung Yun Cho
Sunhwan'gi
Background:The several kinds of coronary stents havve proven successful in theirrole to treat acute or subacute closures after balloon angioplasty as well as to reduce the restenosis rate in de novo lesions. However, investigations continue in order to develop an ideal stent with a strong, highly flexible, radial force, especially useful in cases of tortuous vessels, lesions at bends, and lesions distal to previously deployed stents. The NIR stent is a recently developed balloon-expandable, stainless- steel, slotted tube stent; it is designed for improved flexibility with a higher radial force when compared with the traditional Palmaz-Schatz stent. We report the immediate results of our experience with the NIR stent. The purpose of the present study was to assess the feasibility, safety and efficacy of the deployment of manually crimped NIR stents in patients with complex coronary anatomy as well as the clinical outcomes within the first month. Methods:Between January and July 1997, 143 NIR stents were implanted in the coronary arteries of 124 patients(male 76%, mean age 56±10 years. Sixty-one patients had UAP, 43 had SA, and 20 patients had AMI. Results: 1 Indications of stenting were de novo lesions in 123(95% and restenosis lesion in 6(5%. 2 Frequency of used stent length was 16mm in 65 cases(46%, 32mm in 60 cases(42%, 25 mm in 12 cases(8%, and 9mm in 6 cases(4%. 3 Single stents were implanted in 115(89% lesions, and overlapping stenting with 2nd NIR stents in 14(11% lesions.
Coronary Arterial Remodeling in Athersclerotic Disease: An Intravascular Ultrasonic Study in vivo
Nam Ho Lee, Yangsoo Jang, Dong Soo Kim, Donghoon Choi, Bum‐Kee Hong, Hyun Seung Kim, Sung Soon Kim, Myeong Kon Kim
Sunhwan'gi
Background:Adaptive remodeling of the wall of diseased arterial segments occurs to compensate for the accumulation of atherosclerotic plaque. Histopathologic studies and intraoperative high-frequency epicardial coronary ultrasound imaging as well as intracoronary ultrasound imaging have shown that human coronary arteries enlarge in parallel with the formation of atherosclerotic plaque. Therefore, the lumen area is preserved until the progressive accumulation of plaque exceeds the compensatory mechanisms of the vessel. In 1995, however, Pastercamp et al. reported that arterial wall constriction (shrinkage) or inadequate enlargement may be a different mechanism associated with the development of severe arterial lumen narrowing in addition to plaque proliferation. The aim of this study is to examine what extent of de novo native coronary arterial stenosis is accompanied by compensatory enlargement and to find the predictors of inadequate remodeling with intravascualr ultrasound. Methods:Fifty eight patients were enrolled from February 1997 through October 1997. Patients who had the lesion of more than 50% stenosis of minimal luminal diameter in coronary angiography were indicated. The lesion which was located in the ostium or was very tortuous or angulated was excluded. The lesion which had the history of balloon angioplasty or stent insertion was also excluded. We used 20 MHz endosonic intravascular ultrasound catheter. We measured EEM area (External Elastic Membrane area), lumen area and plaque plus media area and analysed plaque characteristics. Results:1) Fifty-eight consecutive patients (43 men, 15 women;mean age 55.4 years, range 33 to 78)who had not undergone previous catheter intervention were studied with a single intravascular ultrasound system. 2) Among 58 patients, 20 patients (35%) had acute myocardial infarction, 30 patients (52%) unstable angina, 6 patients (10%) stable angina and 2 patients (3%) old myocardial infarction. Lesions were located at the left anterior descending arteries in 29 patients (50%), right coronary arteries in 21 patients (36%) and left circumflex coronary artery in 8 patients (14%). 3) Compensatory enlargement was observed in 19 (32%) of 58 lesions and inadequate compensatory enlargement in 39 (68%). 4) EEM and plaque areas at lesion site of compensatory enlargement group were significantly larger than those of inadequate enlargement group (p<0.05). 5) Risk factors for coronary arterial disease including 논문접수일:1998년 2월 2일 심사완료일:1998년 7월 21일 교신저자:이남호, 210-701 강원도 강릉시 내곡동 522 관동대학교 의과대학 내과학교실 전화) (0391) 649-7466, 전송) (0391) 41-1074 E-mail:namholee@hanmail.net
