발행물

전체 논문

114

1

Engineered lipid nanoparticles enable therapeutic gene silencing of GTSE1 for the treatment of liver fibrosis
이혁진, Michaela Jeong, Sumin Shin, Gyeongseok Lee, Yeji Lee, Seo Bhin Park, Jisoo Kang, Young-Sun Lee, Wonhyo Seo
JOURNAL OF CONTROLLED RELEASE, 2024

2

Optimization of polyethylene glycol shielding and mannose density on the lipid nanoparticles for efficient delivery to macrophages and spleens
이혁진, Sangho Yeo, Hyeondo Lee, Junhyuk Lee, Hyejung Mok
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2024

3

GTSE1-driven ZEB1 stabilization promotes pulmonary fibrosis through the epithelial-to-mesenchymal transition
Hyukjin Lee, Hee Jin, So-Yeon Park, Ji Eun Lee, Hangyeol Park, Michaela Jeong, Jaeho Cho, Yun-Sil Lee1
MOLECULAR THERAPY, 2024

4

Innate immune responses against mRNA vaccine promote cellular immunity through IFN-β at the injection site
이혁진, Myungsun Park, C. Han Li, Taeyoung Lee, Jung-Ah Lee, You-Me Kim, Dokeun Kim, You-Jin Kim, Jinah Yeo, Jong-Eun Park, V. Narry Kim, Seongryong Kim, Ji Hyang Jeon, Myeonghwan Kim, Yeji Lee, Yun-Ho Hwang
NATURE COMMUNICATIONS, 2024

5

Oligonucleotide therapeutics and their chemical modification strategies for clinical applications
이혁진, Hyunsook Kim, Sujeong Kim, Dayoung Lee, Dahye Lee, Jiyeon Yoon
Journal of Pharmaceutical Investigation, 2024

6

<i>In</i><i> vivo</i> genome editing using 244<i>-cis</i> LNPs and low-dose AAV achieves therapeutic threshold in hemophilia A mice
Hyukjin Lee, Haeshin Lee, Su Cheong Yeom, Jeong Pil Han, Yeji Lee, Jeong Hyeon Lee, Hye Yoon Chung, Geon Seong Lee, Yu Ri Nam, Myeongjin Choi, Kyoung-Sik Moon
MOLECULAR THERAPY NUCLEIC ACIDS, 2023

7

Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety
Seongeun Im, Hyein Jung, Hyukjin Lee, Kyungjin Kim, Joo-Sung Yang, Minjeong Kim, Michaela Jeong, Gyeongseok Lee, Yeji Lee, Jeongeun Park
BIOENGINEERING & TRANSLATIONAL MEDICINE, 2023

8

Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics
이혁진, Yeji Lee, Michaela Jeong, Jeongeun Park, Hyein Jung
EXPERIMENTAL AND MOLECULAR MEDICINE, 2023

9

Lipid nanoparticles (LNPs) for<i> in</i><i> vivo</i> RNA delivery and their breakthrough technology for future applications
이혁진, Michaela Jeong, Yeji Lee, Jeongeun Park, Hyein Jung
ADVANCED DRUG DELIVERY REVIEWS, 2023

10

Anti-glioma effect of ginseng-derived exosomes-like nanoparticles by active blood-brain-barrier penetration and tumor microenvironment modulation
Jianxin Wang, Hyukjin Lee, Jisu Kim, Ying Zhu, Sunhui Chen, Dongdong Wang, Shuya Zhang, Jiaxuan Xia, Shiyi Li, Qiujun QIU
JOURNAL OF NANOBIOTECHNOLOGY, 2023