Novel Strategy To Inhibit Transthyretin Amyloidosis via the Synergetic Effect of Chemoselective Acylation and Noncovalent Inhibitor Release.
Seok Beom Lee, Jaeni Yu, Hyunwoo Kim, Kun Woo Kim, Jong Woo Jeong, Yun Lan Kim, Sung Jean Park, Tae-Sung Koo, Changwook Lee, Ki Bum Hong, Sungwook Choi
J. Med. Chem., 2023
32
A Chemical Tool for Blue Light-Inducible Proximity Photocrosslinking in Live Cells.
Pratyush Kumar Mishra‡, Myeong-Gyun Kang‡, Hakbong Lee, Seungjoon Kim, Subin Choi, Nirmali Sharma, Cheol-Min Park, Jaewon Ko, Changwook Lee*, Jeong Kon Seo*, Hyun-Woo Rhee*
Chem. Sci., 2022
33
Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity.
Sujae Yang‡, Nam Gu Yoon‡, Dongyoung Kim‡, Eunsun Park, So-Yeon Kim, Ji Hoon Lee, Changwook Lee, Byoung Heon Kang, Soosung Kang*
ACS Med. Chem. Lett., 2021
34
Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Darong Kim‡, So-Yeon Kim‡, Dongyoung Kim‡, Nam Gu Yoon, Jisu Yun, Ki Bum Hong, Changwook Lee*, Ji Hoon Lee*, Byoung Heon Kang*, Soosung Kang*
Bioorg Chem., 2020
35
Impaired DNA-binding affinity of novel PAX6 mutations.
Seowhang Lee‡, Seung-Han Lee‡, Hwan Heo, Eun Hye Oh, Jin-Hong Shin, Hyang-Sook Kim, Jae-Ho Jung, Seo Young Choi, Kwang-Dong Choi, Hakbong Lee, Changwook Lee*, Jae-Hwan Choi*
Scientific Reports, 2020
36
Rare Variants of Putative Candidate Genes Associated With Sporadic Meniere's Disease in East Asian Population.
Eun Hye Oh, Jin-Hong Shin, Hyang-Sook Kim, Jae Wook Cho, Seo Young Choi, Kwang-Dong Choi, Je-Keun Rhee, Seowhang Lee, Changwook Lee, Jae-Hwan Choi
Front Neurol., 2020
37
Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as Potent Hsp90 Inhibitors With Selectivity Over TRAP1.
Sejin Jung, Nam Gu Yoon, Sujae Yang, Darong Kim, Won Seok Lee, Ki Bum Hong, Changwook Lee, Byoung Heon Kang, Ji Hoon Lee, Soosung Kang
Bioorg Med Chem Lett., 2020
38
Bright ligand-activatable fluorescent protein for high-quality multicolor live-cell super-resolution microscopy.
Jiwoong Kwon, Jong-Seok Park, Minsu Kang, Soobin Choi, Jumi Park, Gyeong Tae Kim, Changwook Lee, Sangwon Cha, Hyun-Woo Rhee, Sang-Hee Shim
Nature Communications, 2020
39
Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiae.
Miriam Lee, Yeojin Moon, Sanghwa Lee, Changwook Lee, Youngsoo Jun
FASEB J., 2018
40
Identification of a novel GPR143 mutation in X-linked ocular albinism with marked intrafamilial phenotypic variability.
Jae-Ho Jung, Eun Hye Oh, Jin-Hong Shin, Hyang-Sook Kim, Seo Young Choi, Kwang-Dong Choi, Changwook Lee, Jae-Hwan Choi Choi