Laboratory of Structural Pharmacology & Drug Design
연세대학교 본교(제1캠퍼스) 약학대학
김국래 교수
GPCR Structure
Serotonin Receptors
Cancer Metabolism
발행물
전체 논문
27
1
Constitutive activation mechanism of a class C GPCR
Jinwoo Shin, Junhyeon Park, Jieun Jeong, Jordy Homing Lam, Xingyu Qiu, Di Wu, Kuglae Kim, Joo-Youn Lee, Carol V Robinson, Jaekyung Hyun, Vsevolod Katritch, Kwang Pyo Kim, Yunje Cho
Nature Structural & Molecular Biology, 2024
2
AlphaFold2 structures template ligand discovery
Jiankun Lyu, Nicholas Kapolka, Ryan Gumpper, Assaf Alon, Liang Wang, Manish K Jain, Ximena Barros-Álvarez, Kensuke Sakamoto, Yoojoong Kim, Jeffrey DiBerto, Kuglae Kim, Tia A Tummino, Sijie Huang, John J Irwin, Olga O Tarkhanova, Yurii Moroz, Georgios Skiniotis, Andrew C Kruse, Brian K Shoichet, Bryan L Roth
bioRxiv, 2023
3
Structural studies of serotonin receptor family
Apeksha Parajulee, Kuglae Kim*
BMB reports, 2023
4
Molecular mechanism of biased signaling at the kappa opoid receptor
Amal El daibani*, Joseph M. Paggi*, Kuglae Kim*, Yianni D. Laloudakis*, Petr Popov, Sara M. Bernhard, Brian E. Krumme, Reid H. J. Olsen, Jeffrey Diberto, F. Ivy Carrol, Vsevolod Katritch, Bernhard Wunsch, Ron O. Dror, Tao Che
Nature Communications, 2023
5
Bespoke library docking for 5-HT2a receptor agonists with antidepressant activity
Anat Levit*, Danielle N. Confair*, Kuglae Kim*, Ximena Barros Alvarez*, Ramona M. Rodriguiz, Ying Yang, Oh Sang Kwon, Tao Che, John McCorvey, David N. Kamber, James P. Phelan, Luan Carvalho Martins, William C. Wetsel, Jeffrey F. DiBerto, Sameual T. Slocum, Xi-Ping Huang, Jian Manish Kumar, Willliam C. Wetsel⊺, John. J. Irwin⊺, Georgios Skiniotis⊺, Brian K. Shoichet⊺, Bryan L. Roth⊺, Jonathan A. Ellman⊺
Nature, 2022
6
Unknown
Can Cao*, Ximena Barros-Alvarez*, Shicheng Zhang*, Kuglae Kim*, Marc Andre Damgen, Oulina Panova, Carl-Mikael Suomivuori, Jonathan Fay, Xiofang Zhong, Brian E. Krumm, Ryan Gumpper, Alpay Seven, Michael J. Robertson, Nevan J. Krogan, Ruth Huttenhain, David E Nichols Ron O. Dror, Georgios Skiniotis
bioRxiv,
7
Signaling snapshots of 5-HT2BR Activated by the Prototypical Psychedelic LSD
Mikael Suomivuori, Jonathan Fay, Xiofang Zhong, Brian E. Krumm, Ryan Gumpper, Alpay Seven, Michael J. Robertson, Nevan J. Krogan, Ruth Huttenhain, David E Nichols, Ron O. Dror, Georgios Skiniotis, Bryan Roth
Neuron, 2022
8
Inactive and active state structures template selective tools for the human 5-HT5A receptor
Shicheng Zhang, He Chen, Chengwei Zhang, Ying Yang, Petr Popov, Jing Liu, Brian E Krumm, Can Cao, Kuglae Kim, Yan Xiong, Vsevolod Katritch, Brian K Shoichet, Jian Jin, Jonathan F Fay, Bryan L Roth
Nature Structural & Molecular Biology, 2022
9
Structure, Function and Pharmacology of Human Itch GPCRs
Can Cao, Hye Jin Kang, Isha Singh, He Chen, Chengwei Zhang, Wenlei Ye, Jing Liu, Ryan H. Gumpper, Brian J. Bender, Sam Slocum, Brian E. Krumm, Katherine Lansu, John D. McCorvy, Wesley K. Kroeze, Jeffrey F. DiBerto, Reid H. J. Olsen, Xi-Ping Huang, Shicheng Zhang, Yongfeng Liu, Kuglae Kim, Lily Y. Jan, Jian Jin, Brian Shoichet, Jonathan F. Fay, Bryan L. Roth
Nature, 2021
10
Structure of a Hallucinogen activated Gq-Coupled 5-HT2A Serotonin Receptor
Kuglae Kim, Tao Che, Ouliana Panova, Jeffrey F. DiBerto, Jiankun Lyu, Brian E. Krumm, Daniel Wacker, Michael J. Robertson, Alpay B. Seven, David E. Nichols, Brian K. Shoichet, Georgios Skiniotis, Bryan L. Roth
Cell, 2020