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인공생체분자합성연구실

부산대학교 본교(제1캠퍼스) 화학과

고민섭 교수

Genetic Code Expansion

Bispecific Small Molecule Engineering

Translation System

발행물

전체 논문

48

21

Structural basis for differential activities of enantiomeric PPARγ agonists: Binding of S35 to the alternate site
Jang, J. Y., Koh, M., Bae, H., An, D. R., Im, H. N., Kim, H.S., Yoon, J. Y., Yoon, H. J., Han, B. W., Park, S. B., Suh, S. W.
Biochim. Biophys. Acta – Proteins and Proteomics, 2017

22

Generation of an orthogonal protein-protein interface with a noncanonical amino acid
Koh, M., Nasertorabi, F., Han, G. W., Stevens, R. C., Schultz, P. G.
J. Am. Chem. Soc., 2017

23

A novel small-molecule agonist of PPAR-γ potentiates an anti-inflammatory M2 glial phenotype
Song, G. J., Nam, Y., Jo, M., Jung, M., Koo, J. Y., Cho, W., Koh, M., Park, S. B., Suk, K.
Neuropharmacology, 2016

24

, 2016

25

Investigation of specific binding proteins to photoaffinity linkers for efficient deconvolution of target protein
Park, J., Koh, M., Koo, J. Y., Lee, S., Park, S. B.
ACS Chem. Biol., 2016

26

A novel non-agonist peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand UHC1 blocks PPAR gamma phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity
Choi, S. S., Kim, E. S., Koh, M., Lee, S. J., Lim, D. H., Yang, Y. R., Jang, H. J., Seo, K. A., Min, S. H., Lee, I. H., Park, S. B., Suh, P. G., Choi, J. H.
J. Biol. Chem., 2014

27

Phenotypic screening to identify small-molecule enhancers for glucose uptake: target identification and rational optimization of their efficacy
Koh, M., Park, J., Koo, J. Y., Lim, D., Cha, M. Y., Jo, A., Choi, J. H., Park, S. B.
Angew. Chem. Int. Ed., 2014

28

Inverse agonist of ERRgamma controls Salmonella typhimurium infection by modulating host iron homeostasis
Kim, D. K., Jeong, J. H., Lee, J. M., Kim, K. S., Park, S. H., Kim, Y. D., Koh, M., Shin, M., Jung. Y. S., Kim, H. S., Lee, T. H., Oh, B. C., Kim, J. I., Park, H. T., Jeong, W. I., Lee, C. H., Park, S. B., Min, J. J., Jung, S. I., Choi, S. Y., Choy, H. E., Choi, H. S.
Nat. Med., 2014

29

Total synthesis of eryvarin H and its derivatives and their biological activity as ERRgamma inverse agonist
Koo, J. Y., Oh, S., Cho, S. R., Koh, M., Oh, W. K., Choi, H. S., Park, S. B.
Org. Biomol. Chem., 2013

30

Inverse agonist of nuclear receptor ERRgamma mediates antidiabetic effect through inhibition of hepatic gluconeogenesis
Kim, D. K., Gang, G. T., Ryu, D., Koh, M., Kim, Y. N., Kim, S. S., Park, J., Kim, Y. H., Sim, T., Lee, I. K., Choi, C. S., Park, S. B., Lee, C. H., Koo, S. H., Choi, H. S.
Diabetes, 2013