p21-Activated Kinase 4 and Ischemic Acute Kidney Injury in Mice and Humans
Dr. Hwang Chan Yu
JASN, 2025.02
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p21-Actived Kinase 4 and Ischemic Acute Kidney Injury in Mice and Humans.
Hwang Chan Yu, Byeoung Hoon Chung, Yoejin Kim, Yoonji Lee, Hyunchae Sim, Sangkyu Lee, Hong Pil Hwang, Hee Chul Yu, Seunggyu Jeon, Han-Joo Maeng, Dongyun Shin, Kyung Pyo Kang, Seung-Yong Seo, Eun Ju Bae*, Byung-Hyun Park*
J Am Soc Nephrol., 2025
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PAK4 phosphorylates cyclin dependent kinase 2 to promote the G1/S transition during adipogenesis.
Hwang Chan Yu, Su Hyeon Park, Hye-Jin Jo, Hyunchae Sim, Mi Rin Lee, Gahee Kim, So-Young Park, Yoonji Lee*, Eun Ju Bae*, Byung-Hyun Park*
Exp. Mol. Med., 2025
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Cannabidiol reshapes the gut microbiome to promote endurance exercise in mice.
Si Chen, Yu-Bin Lee, Mi-Young Song, Changjin Lim, Hwangeui Cho, Hyun Joo Shim, Jong-Suk Kim, Byung-Hyun Park, Jeon-Kyung Kim*, Eun Ju Bae*
Exp. Mol. Med., 2025
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Cannabidiol inhibits IgE-mediated mast cell degranulation and anaphylaxis in mice.
Xiaohui Yang, Dohyeon Lee, Hyun-Woo Kim, Byung-Hyun Park, Changjin Lim*, Eun Ju Bae*
Mol. Nutr. Food Res., 2024
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PAK4 counteracts PKA dependent lipolysis by phosphorylating FABP4 and HSL.
Hwang Chan Yu, Yong Geun Jeon, Ann Yae Na, Chang Yeob Han, Mi Rin Lee, Jae Do Yang, Hee Chul Yu, Jung Beom Son, Nam Doo Kim, Jae Bum Kim, Sangkyu Lee*, Eun Ju Bae*, Byung-Hyun Park*
Nat. Metab., 2024
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PAK4 phosphorylates and inhibits AMPKα to control glucose uptake.
Dandan Wu, Hwang Chan Yu, Hye-Na Cha, Soyoung Park, Yoonji Lee, Sun-Jung Yoon, So-Young Park*, Byung-Hyun Park*, Eun Ju Bae*
Nat. Commun., 2024
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p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1.
Min Yan Shi, Hwang Chan Yu, Chang Yeob Han, In Hyuk Bang, Ho Sung Park, Kyu Yun Jang, Jeong Bum Son, Nam Doo Kim, Byung-Hyun Park*, Eun Ju Bae*
Nat. Commun., 2023
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Lycium chinense Miller fruit extract lowers serum liver enzymes in subjects with mild hepatic dysfunction: A randomized, double-blinded, placebo-controlled clinical trial.