발행물

전체 논문

396

1

SiMPl-GS: Advancing Cell Line Development via Synthetic Selection Marker for Next-Generation Biopharmaceutical Production
C. Yoon, E. J. Lee, D. Kim, S. Joung, Y. Kim, H. Jung, Y. G. Kim, G. M. Lee
Adv. Sci., 2024

2

Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production
S. H. Kim, J. Park, S. Shin, S. Shin, D. Chun, Y. G. Kim, J. Yoo, W. K. You, J. S. Lee, G. M. Lee
ACS Synth. Biol., 2024

3

Unraveling Productivity-Enhancing Genes in Chinese Hamster Ovary Cells via CRISPR Activation Screening Using Recombinase-Mediated Cassette Exchange System
M. Baek, C. L. Kim, S. H. Kim, K. J. la Cour Karottki, H. Hefzi, L. M. Grav, L. E. Pedersen, N. E. Lewis, J. S. Lee, G. M. Lee
Metabolic Eng., 2024

4

Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies
Noh, S. M., Shin, S., Lee, G. M.
Scientific Reports, 2018

5

Untangling the mechanism of 3‐methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3‐methyladenine
Baek E, Lee JS, Lee GM
Biotechnology and Bioengineering, 2018

6

Proteomic Analysis of Host Cell Protein Dynamics in the Culture Supernatants of Antibody-Producing CHO Cells
Park, J. H. et al
Sci. Rep., 2017

7

Recombinase-Mediated Cassette Exchange-Based CRISPR Activation Screening Identifies Hyperosmotic Stress-Resistant Genes in Chinese Hamster Ovary Cells
M. Baek, S. Kweon, Y. Kim, N. E. Lewis, J. S. Lee, G. M. Lee
ACS Synth. Biol., 2025

8

Improving Recombinant Antibody Production Using FcBAR: An In Situ Approach to Detect and Amplify Protein-Protein Interactions
M. Y. M. Wu, F. Rocamora, M. Samoudi, C. M. Robinson, C.-C. Kuo, N. Pristovšek, L. M. Grav, H. F. Kildegaard, G. M. Lee, A. R. Campos, N. E. Lewis
Metabolic Eng., 2025

9

Multiplex Genome Editing Eliminates the Warburg Effect without Impacting Growth Rate in Mammalian Cells
H. Hefzi, I. Martinez-Monge, I. M. de Mas, N. L. Cowie, A. G. Toledo, S. M. Noh, K. J. la Cour Karottki, M. Decker, J. Arnsdorf, J. M. Camacho-Zaragoza, S. Kol, S. Schoffelen, N. Pristovšek., A. H. Hansen, A. A. Miguez, S. P. Bjorn, K. K. Brøndum, E. M. Javidi, K. L. Jensen, L. Stangl, E. Kreidl, T. B. Kallehauge, D. Ley, P. Ménard, H. M. Petersen, Z. Sukhova, A. Bauer, E. Casanova, N. Barron, J. Malmström, L. K. Nielsen, G. M. Lee, H. F. Kildegaard, B. G. Voldborg, N. E. Lewis.
Nat. Metab., 2025

10

Genome-Scale CRISPR Screenings for Insights into Gene Essentiality and Functionality in CHO Cells
S. W. Shin, S. H. Kim, A. Gasselin, G. M. Lee, J. S. Lee
Scientific Data, 2025