Fibroblasts genetically engineered to secret cytokines can suppress tumor growth and induce antitumor immunity to a murine glioma in vivo.

Selectivity of desulfurization activity of Desulfovibrio desulfuricans M6 on different petroleum products.

Non random activation of endogenous interleukin-2(IL-2), IL-2 receptor and IL-2 receptor genes after transfection of mouse fibroblasts with cDNA for the chain of the human IL-2 receptor.

Prolonged survival of mice with glioma injected intracerebrally with double cytokine-secreting cells.

Interleukin-2-secreting mouse fibroblasts transfected with genomic DNA from murine melanoma cells prolong the survival of mice with melanoma.

Immunization of mice with allogeneic fibroblasts genetically modified for IL-2-secretion and the expression of melanoma-associated antigens stimulates predetermined classes of antimelanoma effector cells.

MHC antigen-expression by melanomas recovered from mice treated with allogeneic mouse fibroblasts genetically modified for IL-2-secretion and the expression of melanoma-associated antigens.

Independent pathways are involved in the induction of antimelanoma responses in C57BL/6 mice immunized with interleukin-2-secreting allogeneic mouse fibroblasts expressing melanoma associated antigens.

Immunization with interleukin-2-secreting allogeneic mouse fibroblasts expressing melanoma associated antigens prolongs the survival of tumor-bearing mice.

Immunity to B16 melanoma in mice immunized with IL-2-secreting allogeneic mouse fibroblasts expressing melanoma associated antigens.