Loss of the Set2 histone methyltransferase increases cellular lifespan in yeast cells

The RNA polymerase II Rpb4/7 subcomplex regulates cellular lifespan through an mRNA decay process

Cellular aging is associated with increased ubiquitylation of histone H2B in yeast telomeric heterochromatin

Role of yeast JmjC-domain containing histone demethylases in actively transcribed regions

IMP dehydrogenase is recruited to the transcription complex through serine 2 phosphorylation of RNA polymerase II

A Bre1-associated Protein, Large 1 (Lge1), Promotes H2B Ubiquitylation during the Early Stages of Transcription Elongation

A novel gamma-lactam-based histone deacetylase inhibitor potently inhibits the growth of human breast and renal cancer cells

Rapamycin Down-Regulates Inducible Nitric Oxide Synthase by Inducing Proteasomal Degradation

Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase II.

Reversine increases the plasticity of lineage-committed cells toward neuroectodermal lineage.