,

Isocitrate dehydrogenase 2 inhibition stimulate vascular inflammation in response to oxidative stress

,

CR6 interacting factor-1 linked with tetrahydrobiopterin deficiency and endothelial nitric oxide synthase uncoupling

,

The APE1/Ref-1 inhinits inorganic phosphate-induced vascular calcification in vascular smooth muscle cells and exvivo aorta

,

Protein kinase C beta Ⅱinduces endothelial dysfunction via mitochondreal ROS generation in HUVECs

,

The reducing APE1/Ref-1 causes a conformational change in inflammation mediated receptor affecting its inhibition of inflammation