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87

1

PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification
Kang H, Park S, Jo A, Mao X, Kumar M, Park CH, Ahn JY, Lee Y, Choi JY, Lee YS, Dawson VL, Dawson TM, Kam TI#, Shin JH#
EMBO Rep., 2023.11

2

MEK1/2  inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer's Disease
Chun YS, Kim MY, Lee SY, Kim MJ, Hong TJ, Jeon JK, Ganbat D, Kim HT, Kim SS, Kam TI #, Han S#
Mol Psychiatry, 2022.11

3

PAAN/MIF Nuclease Inhibition Prevents Neurodegeneration in Parkinson’s Disease
Park H*, Kam TI*, Peng H, Chou SC, Mehrabani-Tabar AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao Choi Y, Aggarwal A, Chang S, Kim H, Byun J, Liu JO, Dawson TM, Dawson VL
Cell, 2022.05

4

Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin
Kam TI, Park H, Chou SC, Vranken JGV, Mittenbühler MJ, Kim H, A M, Choi YR, Biswas D, Wang J, Shin Y, Loder  A, Karuppagounder SS, Wrann CD, Dawson VL, Spiegelman BM, Dawson TM
Proc Natl Acad Sci USA, 2022.09

5

PARIS farnesylation prevents neurodegeneration in models of Parkinson’s disease
Jo A*, Lee Y*, Kam TI*, Kang SU, Neifert S, Karuppagounder SS, Khang R, Kang H, Park H, Chou SC, Oh S, Jian H, Swing DA, Ham S, Pirooznia S, Umanah GKE, Mao X, Kumar M, Ko HS, Kang HC, Lee BD, Lee YI, Andrabi SA, Park CH, Lee JY, Kim H, Kim H, Kim H, Cho JW, Paek SH, Na CH, Tessarollo L, Dawson VL, Dawson TM, Shin JH
Science Translational  Medicine, 2021.07

6

Poly (ADP-ribose) drives pathologic a-synuclein neurodegeneration in Parkinson’s disease
Kam TI*, Mao X*, Park H*, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmarchari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, Bekris LM, Leverenz JB, Pantelyat A, Ko HS, Rosenthal LS, Dawson TM, Dawson VL
Science, 2018.11

7

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
Yun SP*, Kam TI*, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke V, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S, Dawson TM, Ko HS
Nature Medicine, 2018.07

8

In-Depth Cell-Type-Specific Proteome Landscape of the Brain from Human Amyloid-β Overexpression Mouse Model
Ryu T, Kim SY, Thuraisamy T, Shin J, Jang Y, Kam TI, Na CH
Advanced Science, 2025.05

9

Exploring [11C]CPPC as a CSF1R-targeted PET imaging marker for early Parkinson's disease severity
Mills KA, Du Y, Coughlin JM, Foss CA, Horti AG, Jenkins KR, Skorobogatova Y, Spiro E, Motley CS, Dannals RF, Lesniak WG, Song JJ, Choi YR, Redding-Ochoa J, Troncoso JC, Dawson VL, Kam TI, Pomper MG, Dawson TM
J Clin Invest, 2025.04

10

α-Synuclein pathology as a target in neurodegenerative diseases
Park H, Kam TI*, Dawson VL, Dawson TM
Nature Reviews Neurology, 2024