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전체 논문

87

11

Poly ADP-ribose signaling is dysregulated in Huntington disease
Maiuri T, Bazan CB, Harding RJ, Begeja N, Kam TI, Byrne LM, Rodrigues FB, Warner MM, Neuman K, Mansoor M, Badiee M, Dasovich M, Wang K, Thompson LM, Leung AKL, Andres SN, Wild EJ, Dawson TM, Dawson VL, Arrowsmith CH, Truant R
Proc Natl Acad Sci USA, 2024.10

12

Dopamine-conjugated extracellular vesicles induce autophagy in Parkinson's disease
Sul JH, Shin S, Kim HK, Han J, Kim J, Son S, Lee J, Baek SH, Cho Y, Lee J, Park J, Ahn D, Park S, Palomera LF, Lim J, Kim J, Kim C, Han S, Chung KY, Lee S, Kam TI, Lee Y, Kim J, Park JH, Jo DG
J Extracell Vesicles, 2024.12

13

Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate
Bae JH*, Jo A*, Cho SC*, Lee YI*, Kam TI*, You CL, Jeong HJ, Kim H, Jeong MH, Jeong Y, Ha YW, Kim YS, Kim J, Woo SH, Kim MS, Shin ES, Song SO, Kang H, Khang R, Park S, Park J, Dawson VL, Dawson TM#, Park SC#, Shin JH#, Kang JS#
Sci Transl Med, 2023.08

14

Production of α-synuclein preformed fibrils (PFF)
Kam TI, Chen R, Dawson VL, Dawson TM
Protocols.io, 2023

15

Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease
Kim SH, Cho YS, Kim Y, Park J, Yoo SM, Gwak J, Kim Y, Gwon Y, Kam TI, Jung YK
Autophagy, 2023.02

16

Pathogenic Role of RAGE in Tau Transmission and Memory Deficits
Kim Y, Park H, Kim Y, Kim SH, Lee JH, Yang H, Kim SJ, Li CM, Lee H, Na DH, Moon S, Shin Y, Kam TI, Lee HW, Kim S, Song JJ, Jung YK
Biol Psychiatry, 2023.05

17

MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer's Disease
Chun YS, Kim MY, Lee SY, Kim MJ, Hong TJ, Jeon JK, Ganbat D, Kim HT, Kim SS, Kam TI #, Han S#
Mol Psychiatry, 2022.11

18

Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein
Sterling JK*, Kam TI*, Guttha S, Park H, Baumann B, Mehrabani-Tabari AA, Schultz H, Anderson B, Alnemri A, Chou SC, Troncoso JC, Dawson VL, Dawson TM, Dunaief J
Cell Rep, 2022.02

19

Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease
Panicker N, Kam TI, Wang H, Neifert S, Chou SC, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, Mao X, Xu E, Karuppagounder SS, Hsu ET, Kang SU, Pletnikova O, Troncoso J, Dawson VL, Dawson TM
Neuron, 2022.08

20

Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins
Gao J, Mewborne QT, Girdhar A, Sheth U, Coyne AN, Punathil R, Kang BG, Dasovich M, Veire A, DeJesus Hernandez M, Liu S, Shi Z, Dafinca R, Fouquerel E, Talbot K, Kam TI, Zhang YJ, Dickson D, Petrucelli L, van Blitterswijk M, Guo L, Dawson TM, Dawson VL, Leung AKL, Lloyd TE, Gendron TF, Rothstein JD, Zhang K
Sci Transl Med, 2022.09