Pharmacological targeting of mitophagy via ALT001 improves herpes simplex virus 1 (HSV1)-mediated microglial inflammation and promotes amyloid β phagocytosis by restricting HSV1 infection.
Soo-Jin Oh, Young Yeon Kim, Ruiying Ma, Seok Tae Choi, Se Myeong Choi, Jong Hyun Cho, Ji-Yeun Hur, Yongjin Yoo, Kihoon Han, Hosun Park, Jeanho Yun*, Ok Sarah Shin
Theranostics, 2025
2
A novel marine-derived mitophagy inducer ameliorates mitochondrial dysfunction and thermal hypersensitivity in paclitaxel-induced peripheral neuropathy.
Im SW, Jeong DJ, Kim EM, Choi JH, Jang HJ, Kim YY, Um JH, Lee JH, Lee YJ, Lee KM, Choi DB, Yoo EH, Lee HS, Yun J*
Br J Pharmacol, 2024
3
The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress.
Jeong DJ, Um JH, Kim YY, Shin DJ, Im SW, Lee KM, Lee YH, Lim DS, Kim D, Yun J*
Exp Mol Med, 2024
4
Varicella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity.
Selective induction of Rab9-dependent alternative mitophagy using a synthetic derivative of isoquinoline alleviates mitochondrial dysfunction and cognitive deficits in Alzheimer’s disease models.
Um JH, Shin DJ, Choi SM, Nathan A, Kim YY, Lee DY, Jeong DJ, Kim DH, Kim K, Kim HY, Nah J, Jeong JH, Yoo E, Shin HK, Park HT, Jo J, Cho JH, Yun J*
Theranostics, 2024
6
Berberine Induces Mitophagy through Adenosine Monophosphate-Activated Protein Kinase and Ameliorates Mitochondrial Dysfunction in PINK1 Knockout Mouse Embryonic Fibroblasts.
Um JH, Lee KM, Kim YY, Lee DY, Kim E, Kim DH, Yun J*
Int. J. Mol. Sci., 2023
7
Glucose-mediated mitochondrial reprogramming by cholesterol export at TM4SF5-enriched mitochondria-lysosome contact sites.
Kim JE, Park SY, Kwak C, Lee Y, Song DG, Jung JW, Lee H, Shin EA, Pinanga Y, Pyo KH, Lee EH, Kim W, Kim S, Jun CD, Yun J, Choi S, Rhee HW, Liu KH, Lee JW
Cancer Commun (Lond), 2023
8
The Natural Alkaloid Palmatine Selectively Induces Mitopha-gy and Restores Mitochondrial Function in an Alzheimer's Disease Mouse Model.
Lee DY, Lee KM, Um JH, Kim YY, Kim DH, Yun J*
Int. J. Mol. Sci., 2023
9
PINK1 and Parkin Ameliorate the Loss of Motor Activity and Mitochondrial Dysfunction Induced by Peripheral Neuropathy-Associated HSPB8 Mutants in Drosophila Models.
Kyong-Hwa Kang, Ji Eun Han, Hyunjin Kim, Sohee Kim, Young Bin Hong, Jeanho Yun, Soo Hyun Nam, Byung-Ok Choi, Hyongjong Koh
Biomedicines, 2023
10
COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20.
Sang-Heum Han, Young Hee Kim, Su-Jeong Park, Jun-Gi Cho, Yoon Kyung Shin, Young Bin Hong, Jeanho Yun, Jin-Yeong Han, Hwan Tae Park, Joo-In Park