Discovery of 5-methyl-N-(2-arylquinazolin-7-yl)isoxazole-4-carboxamide analogues as highly selective FLT3 inhibitors

Discovery of 1-Pyrimidinyl-2-Aryl-4,6-Dihydropyrrolo [3,4-d]Imidazole-5(1H)-Carboxamide as a Novel JNK Inhibitor

Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives as a novel selective inhibitor scaffold of JNK3

Conformational restriction of a type II FMS inhibitor leading to discovery of 5-methyl-N-(2-aryl-1H-benzo[d]imidazo-5-yl)isoxazole-4-carboxamide analogues as selective FLT3 inhibitors

Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as a highly selective and potent BRAFV600E and CRAF inhibitor

Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone

Design, synthesis, and in vitro evaluation of N-(3-(3-alkyl-1H-pyrazol-5-yl) phenyl)-aryl amide for selective RAF inhibition

Discovery of novel 4-aryl-thieno[1,4] diazepin-2-one derivatives targeting multiple protein kinases as anticancer agents

Novel scaffold evolution through combinatorial 3D-QSAR model studies of two types of JNK3 inhibitors

Nec-1 alleviates cognitive impairment with reduction of A and tau abnormalities in APP/PS1 mice