Design, synthesis, and in vitro evaluation of N-(3-(3-alkyl-1H-pyrazol-5-yl) phenyl)-aryl amide for selective RAF inhibition

Discovery of novel 4-aryl-thieno[1,4] diazepin-2-one derivatives targeting multiple protein kinases as anticancer agents

Novel scaffold evolution through combinatorial 3D-QSAR model studies of two types of JNK3 inhibitors

Nec-1 alleviates cognitive impairment with reduction of A and tau abnormalities in APP/PS1 mice

Discovery of highly selective CRAF inhibitors, 3-carboxamido-2H-indazole-6-arylamide: In silico FBLD design, synthesis and evaluation

Synthesis of stereochemically diverse cyclic analogs of tubulysins

Discovery of 4-arylamido 3-methyl isoxazole derivatives as novel FMS kinase inhibitors

De Novo Design and Synthesis of a γ-Turn Peptidomimetic Scaffold and Its Application as JNK3 Allosteric Ligand

Click approach to the discovery of 1,2,3-triazolylsalicylamides as potent Aurora kinase inhibitors

Design, synthesis and biological evaluation of benzyl 2-(1H-imidazole-1-yl) pyrimidine analogues as selective and potent Raf inhibitors