Knockout of Proapoptotic BAX and BAK1 Genes in HEK293T Cells Enhances Adeno-Associated Virus (AAV) Production Regardless of AAV Serotype
S. Park, S. Shin, G. Han, G. M. Lee
Biotechnol. J., 2025
12
Development, Physico-Chemical Characterization, and in Vivo Stability of a Novel Aglycosylated Monoclonal Antibody Targeting FAM19A5
W. K. Kim, J. Y. Seong, G. M. Lee
Biotechnol. Bioproc. Eng., 2024
13
Sialyllactose Supplementation Enhances Sialylation of Fc-Fusion Glycoprotein in Recombinant Chinese Hamster Ovary Cell Culture
H. M. Lee, T. H. Kim, J. H. Park, N. Y. Heo, H. S. Kim, D. E. Kim; M. K. Kim, G. M. Lee, J. You, Y. G. Kim
J. Biotechnol., 2024
14
Enhancing the Production of Adeno-Associated Virus (AAV)2 and AAV9 with High Full Capsid Ratio in HEK293 Cells through Design-of-Experiment Optimization of Triple Plasmid Ratio
S. Park, S. Shin, H. Lee, J. H. Jang, G. M. Lee
Biotechnol. J., 2024
15
Effects of Autophagy-Inhibiting Chemicals on Sialylation of Fc-Fusion Glycoprotein in Recombinant Chinese Hamster Ovary Cell Culture
H. M. Lee, J. H. Park, T. H. Kim, H. S. Kim, D. E. Kim; M. K. Lee, J. You, G. M. Lee, Y. G. Kim
Appl. Microbiol. Biotechnol., 2024
16
Extraction of an Outer Membrane Protein Pertactin from Bordetella pertussis with Urea for the Production of Acellular Pertussis Vaccine
J. H. Moon, J. K. Park, B. Y. Park, H. J. Jeon, G. S. Choi, G. M. Lee
Biotechnol. Bioproc. Eng., 2024
17
Genome-Wide CRISPR/Cas9 Knockout Screening to Mitigate Cell Growth Inhibition Induced by Histone Deacetylase Inhibitors in Recombinant CHO Cells
D. Kim, S. H. Kim, C. Yoon, G. M. Lee
Biotechnol. Bioeng., 2023
18
In-Vitro Induction of In-Vivo-Relevant Stellate Astrocytes in 3D Brain-Derived, Decellularized Extracellular Matrices
S. Han, J. Kim, S. H. Kim, W. Youn, J. Kim, G. Y. Ji, S. Yang, J. Park, G. M. Lee, Y. Kim, I. S. Choi
Acta Biomater., 2023
19
Enhancing the Production of Recombinant Human TGF-β1 Through an Understanding of TGF-β1 Synthesis, Signaling, and Endocytosis in CHO Cells
K. Kim, Y. S. Kim, J. W. Jang, G. M. Lee
Biotechnol. J., 2023
20
Identification of Hyperosmotic Stress-Responsive Genes in Chinese Hamster Ovary Cells via Genome-Wide Virus-Free CRISPR/Cas9 Screening
S. H. Kim, S. Shin, M. Baek, K. Xiong, K. J. la C. Karottki, H. Hefzi, L. M. Grav, L. E. Pedersen, H. F. Kildegaard, N. E. Lewis, J. S. Lee, G. M. Lee